Antibiotics. Origin, Nature and Properties by Tadeusz Korzybski

By Tadeusz Korzybski

Antibiotics: starting place, Nature and houses, quantity I is a scientific assurance of the resources, kinds, and homes of the antibiotics. This e-book is prepared into major components encompassing thirteen chapters.
This publication considers the antibiotics in accordance with their resources. It describes the antibiotics produced by means of micro organism, Actinomycetes,Fungi imperfecti, Basidiomycetes, algae, lichens and eco-friendly vegetation, and people from animal resources. This workforce of antibiotics contains, streptomycin, the tetracyclines, chloromycetin, the macrolide relatives of compounds of which erythromycin, magnamycin and spiramycin are individuals, and the antifungal polyene compounds. The individuals of every staff are prepared in response to their chemical and organic similarity. Sections on every one antibiotic current entire info, together with the identify, description of the manufacturing lines, composition of the media, tools of tradition, isolation and purification of the antibiotic precept, its actual and chemical homes, antibiotic spectrum, toxicity for laboratory animals, result of therapy of experimental infections, and attainable medical functions.
This booklet is of price to researchers and staff in a variety of clinical fields.

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By Tadeusz Korzybski

Antibiotics: starting place, Nature and houses, quantity I is a scientific assurance of the resources, kinds, and homes of the antibiotics. This e-book is prepared into major components encompassing thirteen chapters.
This publication considers the antibiotics in accordance with their resources. It describes the antibiotics produced by means of micro organism, Actinomycetes,Fungi imperfecti, Basidiomycetes, algae, lichens and eco-friendly vegetation, and people from animal resources. This workforce of antibiotics contains, streptomycin, the tetracyclines, chloromycetin, the macrolide relatives of compounds of which erythromycin, magnamycin and spiramycin are individuals, and the antifungal polyene compounds. The individuals of every staff are prepared in response to their chemical and organic similarity. Sections on every one antibiotic current entire info, together with the identify, description of the manufacturing lines, composition of the media, tools of tradition, isolation and purification of the antibiotic precept, its actual and chemical homes, antibiotic spectrum, toxicity for laboratory animals, result of therapy of experimental infections, and attainable medical functions.
This booklet is of price to researchers and staff in a variety of clinical fields.

Show description

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Extra info for Antibiotics. Origin, Nature and Properties

Sample text

1951, 192, 663. DIPLOCOCCIN Diplococcin, the antibiotic properties of which were first discovered by Whitehead, was isolated in 1944 by Oxford from a strain of Streptococcus lactis grown on Niveu medium containing casein hydrolysate, salts, growth factors and sucrose. T h e active substance was obtained after removing the bacteria by centri­ fuging and evaporating the culture fluid in vacuo at temperature below 6 0 ° C , extracting the sediment with a cold, dilute solution of acetic acid, and finally precipitating it from the acid solution by adding a m m o n i u m sulphate to 60% saturation (Oxford).

In white mice injections of 100 mg of mycobactocidin per kg body weight were not observed to produce any toxic symptoms. Fifteen subcutaneous injec­ tions of 100 mg per kg body weight each during 30 days did not appear to give rise to any toxic symptoms or visceral lesions in the animals. An antagonistic action of staphylococci on other species of micro-organisms has been observed in the past century (Doehle, L o d e , cited according to Florey). Magrassi and Spiga (1946) and Gardner (1949) isolated a toxic antibiotic from a strain of Staphylococcus aureus.

L: {Serratia marcescens). C. R. 6, 1 3 1 . ( I n R u s s i a n ) . 1937, U . F . : Recovery of prodigiosin. U . S . P a t . , 2 6 6 7 4 9 2 R I C H T ER 1 9 5 0 , 46, 2 2 0 . immitis in vitro. Proc. Soc. Exp. 1 9 3 0 , 191, 4 9 7 . N A K H I M O V S K A YM N A G ER von F : T h e antibiotic activity of violacein, p r o d i g i o s i n and V. S A ND DE Bacteriol, M o Y C H O W . : T h e formation of p i g m e n t b y Bacterium Acad. Bestandteile 1 9 3 2 , 107, 3 3 7 . 656. and H. C. phthiocol. J.

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