By G E W and O'Connor, M Eolstenholme
Chapter 1 Chairman's beginning comments (pages 1–3): Sir John Eccles
Chapter 2 a few houses of Pyramidal Neurones of the Motor Cortex (pages 4–29): C. G. Phillps
Chapter three Neurophysiological Mechanisms in Cerebral Arousal (pages 30–56): Frederic Bremer
Chapter four Electroencephalogram?Synchronizing buildings within the decrease mind Stem (pages 57–85): J. Magnes, G. Moruzzi and O. Pompeiano
Chapter five Mechanisms of Reticular Deactivation (pages 86–107): P. Dell, M. Bonvallet and A. Hugelin
Chapter 6 Neuronal job in Wakefulness and in Sleep (pages 108–130): M. Verzeano and okay. Negishi
Chapter 7 Neuronal Discharge within the Cat's Motor Cortex in the course of Sleep and Arousal (pages 131–170): Otto Creutzfeldt and Richard Jung
Chapter eight results of Sleep and Waking on task of unmarried devices within the Unrestrained Cat (pages 171–187): Edward V. Evarts
Chapter nine Telencephalic and Rhombencephalic Sleep within the Cat (pages 188–208): M. Jouvet
Chapter 10 A medical, Electroencephalographic and Polygraphic research of Sleep within the Human grownup (pages 209–236): H. Fischgold and B. A. Schwartz
Chapter eleven adjustments of Cortical D.C. Potentials within the Sleep?Wakefulness Cycle (pages 237–259): Heinz Caspers
Chapter 12 Electroencephalographic Detection of Sleep prompted by means of Repetitive Sensory Stimuli (pages 260–283): H. Gastaut and J. Bert
Chapter thirteen Electrographic Responses in snoozing Conditioned Animals (pages 284–306): Vernon Rowland
Chapter 14 Hibernation and Sleep (pages 307–321): Paavo Suomalainen
Chapter 15 Sleep styles on Polar Expeditions (pages 322–328): H. E. Lewis
Chapter sixteen results of Sleep?Deprivation on functionality and Muscle rigidity (pages 329–342): R. T. Wilkinson
Chapter 17 Cortical functionality in the course of Human Sleep (pages 343–348): I. Oswald, Anne M. Taylor and M. Treisman
Chapter 18 the character of Dreaming (pages 349–374): Nathaniel Kleitman
Chapter 19 Sleep and the power Metabolism of the mind (pages 375–396): Seymour S. Kety
Chapter 20 Chairman's last feedback (pages 397–400): Sir John Eccles
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Extra resources for Ciba Foundation Symposium - The Nature of Sleep
This consideration seems to apply with special force to the inhibitory, polarizing action of pyramidal tetanization. For the synaptic linkage of the facilitatory, depolarizing action is evidently the more direct of the two. Thus, a single pyramidal volley may evoke an EPSP with a latency of 3 to 5 msec. (Fig. 5). /sec. (unpublished observations). The excitatory pathway from pyramid to cortex cannot, therefore, have great synaptic complexity, and could even be monosynaptic, if the ascending volleys travelled in small-calibre pyramidal fibres.
Later. /sec. rhythm. 5 mv. c. Later. /sec. rhythm. Firing level - 49 mv. d. Later. Sporadic firing resumed. Firing level - 5 2 MV. Maximum polarization - 62 mv. Cufibrations: Top left: o and - 75 mv. Dots marking antidromic impulses are at I” intervals. FIG. 4. 32 mm. deep from convexity of posterior sigmoid gyrus. , given at one-second intervals, caused depolarizing waves. Top leff: Zero and -7s mv. Meartrrernents: Firing level - 48 to - 49 mv. Maximum polarization - 76 mv. Spike crests + 10 mv.
The first shock excites an antidromic 18 C . G . PHILLIPS impulseandasmallEPSP. Thesecond and third shocks each excite an antidromic impulse followed by an EPSP which generates an impulse. The fourth and fifth antidromic impulses are blocked downstream, giving only “M spikes” (Eccles, 1957). The membrane potential at the moment of generation of the last stunted orthodromic impulse was only -4mv. R. M. Eccles (1955)has seen a similar phenomenon in sympathetic ganglion cells. Granit and Phdlips (1956)found long-lasting inactivation in cerebellar Purkinje cells, which appeared to be due to “hyper-depolarization” by powerful excitatory synaptic drive.